Cryo-TEM (Cryogenic Transmission Electron Microscopy) has many different applications, e.g., minimizing electron beam damage and elemental loss. For instance, for the FeOF/C system used in Li-Ion Batteries, the TEM specimens were cooled to LN2 temperature and imaged with a total electron dose limited to 10⁴ C/cm². [1]

[1] F. Cosandey, Analysis of Li-Ion Battery Materials by Electron Energy Loss Spectroscopy, Microscopy: Science, Technology, Applications and Education, A. Méndez-Vilas and J. Díaz (Eds.), 1662, (2010).